EMD-23831

Single-particle
2.8 Å
EMD-23831
3D View Gallery
Deposition: 14/04/2021
Map released: 13/10/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23831

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7mgz summary report (pdf.gz) Map-7mgz FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Human CTPS1 bound to UTP, AMPPNP, and glutamine

EMD-23831

Single-particle
2.8 Å
EMD-23831
3D View Gallery
Deposition: 14/04/2021
Map released: 13/10/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CTPS1 tetramer
Fitted models: 7mgz

Deposition Authors: Lynch EM , Dimattia MA
Structural basis for isoform-specific inhibition of human CTPS1.
Lynch EM , DiMattia MA, Albanese S , van Zundert GCP, Hansen JM, Quispe JD, Kennedy MA, Verras A, Borrelli K , Toms AV, Kaila N, Kreutter KD, McElwee JJ, Kollman JM
(2021) PNAS , 118
PUBMED: 34583994
DOI: doi:10.1073/pnas.2107968118
ISSN: 1091-6490
ASTM: PNASA6