EMD-23816
Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer
EMD-23816
Single-particle3.87 Å
Deposition: 09/04/2021Map released: 03/11/2021
Last modified: 09/10/2024
Sample Organism:
Influenza A virus,
Homo sapiens
Sample: 310-030-1D06 Fab in complex with an H1 NC99 HA trimer
Fitted models: 7mfg
Deposition Authors: Gorman J
,
Kwong PD
Sample: 310-030-1D06 Fab in complex with an H1 NC99 HA trimer
Fitted models: 7mfg
Deposition Authors: Gorman J
,
Kwong PD
A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination.
Andrews SF ,
Raab JE,
Gorman J ,
Gillespie RA ,
Cheung CSF,
Rawi R,
Cominsky LY ,
Boyington JC,
Creanga A ,
Shen CH,
Harris DR ,
Olia AS,
Nazzari AF,
Zhou T ,
Houser KV ,
Chen GL,
Mascola JR,
Graham BS,
Kanekiyo M ,
Ledgerwood JE,
Kwong PD ,
McDermott AB
(2022) Nat Med , 28 , 373 - 382
,
Raab JE,
Gorman J ,
Gillespie RA ,
Cheung CSF,
Rawi R,
Cominsky LY ,
Boyington JC,
Creanga A ,
Shen CH,
Harris DR ,
Olia AS,
Nazzari AF,
Zhou T ,
Houser KV ,
Chen GL,
Mascola JR,
Graham BS,
Kanekiyo M ,
Ledgerwood JE,
Kwong PD ,
McDermott AB
(2022) Nat Med , 28 , 373 - 382
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM103310 (United States)
- Other private: Simons Foundation (SF349247) (United States)