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EMD-23738

Single-particle
4.76 Å
EMD-23738
3D View Gallery
Deposition: 01/04/2021
Map released: 29/12/2021
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23738
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7mbm summary report (pdf.gz) Map and 7mbm FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode01

EMD-23738

Single-particle
4.76 Å
EMD-23738
3D View Gallery
Deposition: 01/04/2021
Map released: 29/12/2021
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Xenopus laevis, synthetic construct
Sample: MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Mode01)
Fitted models: 7mbm

Deposition Authors: Park SH, Ayoub A
Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes.
Ayoub A, Park SH, Lee YT , Cho US, Dou Y
(2022) Biochemistry , 61 , 1 - 9
PUBMED: 34928138
DOI: doi:10.1021/acs.biochem.1c00603
ISSN: 0006-2960
ASTM: BICHAW