EMD-23681

Single-particle
2.84 Å
EMD-23681
Deposition: 24/03/2021
Map released: 22/03/2023
Obsolete date: 29/03/2023
Last modified: 29/03/2023
Overview

EMD-23681

 This entry has been made obsolete.

Herpes simplex virus 1 polymerase holoenzyme bound to DNA and acyclovir triphosphate in closed conformation

EMD-23681

Single-particle
2.84 Å
EMD-23681
Deposition: 24/03/2021
Map released: 22/03/2023
Obsolete date: 29/03/2023
Last modified: 29/03/2023
Sample Organism: Human alphaherpesvirus 1 strain KOS, synthetic construct
Sample: Herpes simplex virus type 1 polymerase holoenzyme UL30:UL42 in complex with template and primer DNA strands and acyclovir triphosphate
Fitted models: 7m5r

Deposition Authors: Pan J , Abraham J , Coen DM , Shankar S, Yang P, Hogle J

viral polymerase structures in multiple conformations reveal mechanisms for drug selectivity
Pan J , Abraham J , Coen DM , Shankar S, Yang P, Oroszlan G, Mukherjee P, Filman D, Hogle J
To Be Published