EMD-23652

Single-particle
3.2 Å
EMD-23652
3D View Gallery
Deposition: 18/03/2021
Map released: 30/06/2021
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23652

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7m3e summary report (pdf.gz) Map-7m3e FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Asymmetric Activation of the Calcium Sensing Receptor Homodimer

EMD-23652

Single-particle
3.2 Å
EMD-23652
3D View Gallery
Deposition: 18/03/2021
Map released: 30/06/2021
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human extracellular calcium-sensing receptor complexed with negative allosteric modulator NPS-2143 under high calcium high Trp condition
Fitted models: 7m3e

Deposition Authors: Gao Y , Robertson MJ , Zhang C, Meyerowitz JG , Panova O, Skiniotis G
Asymmetric activation of the calcium-sensing receptor homodimer.
Gao Y , Robertson MJ , Rahman SN , Seven AB, Zhang C, Meyerowitz JG , Panova O, Hannan FM , Thakker RV , Brauner-Osborne H , Mathiesen JM , Skiniotis G
(2021) Nature , 595 , 455 - 459
PUBMED: 34194040
DOI: doi:10.1038/s41586-021-03691-0
ISSN: 1476-4687
ASTM: NATUAS