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EMD-23614
SN-407-LRRC8A in MSP1E3D1 lipid nanodiscs (Pose-1)
EMD-23614
Single-particle3.65 Å
Deposition: 12/03/2021Map released: 24/03/2021
Last modified: 23/02/2022
Sample Organism:
Mus musculus
Sample: SN407-LRRC8A in MSP1E3D1 lipid nanodiscs (Pose-1)
Fitted models: 7m17
Deposition Authors: Kern DM
,
Gerber EE ,
Brohawn SG
Sample: SN407-LRRC8A in MSP1E3D1 lipid nanodiscs (Pose-1)
Fitted models: 7m17
Deposition Authors: Kern DM
,
Gerber EE ,
Brohawn SG
Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes.
Gunasekar SK,
Xie L,
Kumar A ,
Hong J,
Chheda PR ,
Kang C,
Kern DM ,
My-Ta C,
Maurer J,
Heebink J,
Gerber EE ,
Grzesik WJ,
Elliot-Hudson M,
Zhang Y,
Key P,
Kulkarni CA ,
Beals JW,
Smith GI,
Samuel I,
Smith JK,
Nau P ,
Imai Y ,
Sheldon RD,
Taylor EB ,
Lerner DJ,
Norris AW ,
Klein S,
Brohawn SG ,
Kerns R ,
Sah R
(2022) Nat Commun , 13 , 784 - 784
,
Hong J,
Chheda PR ,
Kang C,
Kern DM ,
My-Ta C,
Maurer J,
Heebink J,
Gerber EE ,
Grzesik WJ,
Elliot-Hudson M,
Zhang Y,
Key P,
Kulkarni CA ,
Beals JW,
Smith GI,
Samuel I,
Smith JK,
Nau P ,
Imai Y ,
Sheldon RD,
Taylor EB ,
Lerner DJ,
Norris AW ,
Klein S,
Brohawn SG ,
Kerns R ,
Sah R
(2022) Nat Commun , 13 , 784 - 784
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): F32GM128263 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): DP2GM123496 (United States)
- National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK): 1R01DK106009 (United States)