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EMD-23589
Cryo-EM structure of 2909 Fab in complex with 3BNC117 Fab and CAP256.wk34.c80 SOSIP.RnS2 N160K HIV-1 Env trimer
EMD-23589
Single-particle3.91 Å
Deposition: 06/03/2021Map released: 18/08/2021
Last modified: 14/05/2025
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1
Sample: 2909 Fab in complex with 3BNC117 Fab and CAP256.wk34.c80 SOSIP.RnS2 N160K HIV-1 Env trimer
Fitted models: 7ly9
Deposition Authors: Gorman J
,
Kwong PD
Sample: 2909 Fab in complex with 3BNC117 Fab and CAP256.wk34.c80 SOSIP.RnS2 N160K HIV-1 Env trimer
Fitted models: 7ly9
Deposition Authors: Gorman J
,
Kwong PD
Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces.
Lee M ,
Changela A,
Gorman J ,
Rawi R ,
Bylund T ,
Chao CW,
Lin BC,
Louder MK ,
Olia AS,
Zhang B,
Doria-Rose NA,
Zolla-Pazner S ,
Shapiro L ,
Chuang GY,
Kwong PD
(2021) Nat Commun , 12 , 6470 - 6470
,
Changela A,
Gorman J ,
Rawi R ,
Bylund T ,
Chao CW,
Lin BC,
Louder MK ,
Olia AS,
Zhang B,
Doria-Rose NA,
Zolla-Pazner S ,
Shapiro L ,
Chuang GY,
Kwong PD
(2021) Nat Commun , 12 , 6470 - 6470
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM103310 (United States)
- Simons Foundation: SF349247 (United States)