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EMD-23490
Cryo-EM structure of NTD-directed neutralizing antibody 2-17 Fab in complex with SARS-CoV-2 S2P spike
EMD-23490
Single-particle4.47 Å
Deposition: 15/02/2021Map released: 24/03/2021
Last modified: 21/05/2025
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: 2-17 Fab in complex with SARS-CoV-2 S2P spike
Fitted models: 7lqw
Deposition Authors: Gorman J
,
Rapp M
Sample: 2-17 Fab in complex with SARS-CoV-2 S2P spike
Fitted models: 7lqw
Deposition Authors: Gorman J
,
Rapp M
Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cerutti G ,
Guo Y ,
Zhou T ,
Gorman J ,
Lee M ,
Rapp M ,
Reddem ER ,
Yu J,
Bahna F,
Bimela J,
Huang Y,
Katsamba PS ,
Liu L ,
Nair MS ,
Rawi R,
Olia AS,
Wang P ,
Zhang B,
Chuang GY,
Ho DD,
Sheng Z,
Kwong PD ,
Shapiro L
(2021) Cell Host Microbe , 29 , 819 - 833.e7
,
Guo Y ,
Zhou T ,
Gorman J ,
Lee M ,
Rapp M ,
Reddem ER ,
Yu J,
Bahna F,
Bimela J,
Huang Y,
Katsamba PS ,
Liu L ,
Nair MS ,
Rawi R,
Olia AS,
Wang P ,
Zhang B,
Chuang GY,
Ho DD,
Sheng Z,
Kwong PD ,
Shapiro L
(2021) Cell Host Microbe , 29 , 819 - 833.e7
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): U24 GM129539 (United States)
- Other private: SF349247 (United States)