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EMD-23489
Cryo-EM structure of NTD-directed neutralizing antibody 4-8 Fab in complex with SARS-CoV-2 S2P spike
EMD-23489
Single-particle3.25 Å
Deposition: 15/02/2021Map released: 24/03/2021
Last modified: 16/10/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: 4-8 Fab in complex with SARS-CoV-2 S2P spike
Fitted models: 7lqv
Deposition Authors: Gorman J
,
Rapp M
Sample: 4-8 Fab in complex with SARS-CoV-2 S2P spike
Fitted models: 7lqv
Deposition Authors: Gorman J
,
Rapp M
Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite
Cerutti G,
Guo Y,
ZHou T,
Gorman J ,
Lee M,
Rapp M,
Reddem ER,
Yu J,
Bahna F,
Bimela J,
Huang Y,
Katsamba PS,
Liu L,
Nair MS,
Rawi R,
Olia AS,
Wang P,
Zhang B,
Chuang GY,
Ho DD,
Sheng Z,
Kwong PD ,
Shapiro L
(2021) Cell Host Microbe
,
Lee M,
Rapp M,
Reddem ER,
Yu J,
Bahna F,
Bimela J,
Huang Y,
Katsamba PS,
Liu L,
Nair MS,
Rawi R,
Olia AS,
Wang P,
Zhang B,
Chuang GY,
Ho DD,
Sheng Z,
Kwong PD ,
Shapiro L
(2021) Cell Host Microbe
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): U24 GM129539 (United States)
- Other private: SF349247 (United States)