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EMD-23480
Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664
EMD-23480
Single-particle3.61 Å
Deposition: 12/02/2021Map released: 23/02/2022
Last modified: 06/11/2024
Sample Organism:
Human immunodeficiency virus 1,
Lama glama
Sample: HIV-1 Env with llama J3 VHH
Fitted models: 7lpn
Deposition Authors: Gorman J
,
Kwong PD
Sample: HIV-1 Env with llama J3 VHH
Fitted models: 7lpn
Deposition Authors: Gorman J
,
Kwong PD
Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Zhou T ,
Chen L,
Gorman J ,
Wang S ,
Kwon YD,
Lin BC,
Louder MK,
Rawi R,
Stancofski ED,
Yang Y,
Zhang B,
Quigley AF,
McCoy LE,
Rutten L,
Verrips T,
Weiss RA,
Doria-Rose NA,
Shapiro L,
Kwong PD
(2022) Structure , 30 , 862 - 875.e4
,
Chen L,
Gorman J ,
Wang S ,
Kwon YD,
Lin BC,
Louder MK,
Rawi R,
Stancofski ED,
Yang Y,
Zhang B,
Quigley AF,
McCoy LE,
Rutten L,
Verrips T,
Weiss RA,
Doria-Rose NA,
Shapiro L,
Kwong PD
(2022) Structure , 30 , 862 - 875.e4
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM103310 (United States)
- Other private: Simons Foundation (SF349247) (United States)