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EMD-23470
SARS-CoV spike complexed with Fab CV38-142 (2 Fabs bound)
EMD-23470
Single-particle29.3 Å
Deposition: 11/02/2021Map released: 05/05/2021
Last modified: 26/05/2021
Sample Organism:
Severe acute respiratory syndrome-related coronavirus,
Homo sapiens
Sample: SARS-CoV spike complexed with Fab CV38-142 (2 Fabs bound)
Deposition Authors: Bangaru S, Ward AB
Sample: SARS-CoV spike complexed with Fab CV38-142 (2 Fabs bound)
Deposition Authors: Bangaru S, Ward AB
A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection.
Liu H 
,
Yuan M ,
Huang D,
Bangaru S ,
Zhao F,
Lee CD,
Peng L ,
Barman S ,
Zhu X,
Nemazee D,
Burton DR,
van Gils MJ ,
Sanders RW,
Kornau HC,
Reincke SM ,
Pruss H,
Kreye J ,
Wu NC ,
Ward AB,
Wilson IA
(2021) Cell Host Microbe , 29 , 806 - 818.e6
,
Yuan M ,
Huang D,
Bangaru S ,
Zhao F,
Lee CD,
Peng L ,
Barman S ,
Zhu X,
Nemazee D,
Burton DR,
van Gils MJ ,
Sanders RW,
Kornau HC,
Reincke SM ,
Pruss H,
Kreye J ,
Wu NC ,
Ward AB,
Wilson IA
(2021) Cell Host Microbe , 29 , 806 - 818.e6
Grant Support:
- Bill & Melinda Gates Foundation: OPP1170236 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): P01 AI110657 (United States)