EMD-23465

Single-particle
3.9 Å
EMD-23465
3D View Gallery
Deposition: 10/02/2021
Map released: 14/04/2021
Last modified: 02/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23465

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7lok summary report (pdf.gz) Map-7lok FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of CD4 mimetic M48U1 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab

EMD-23465

Single-particle
3.9 Å
EMD-23465
3D View Gallery
Deposition: 10/02/2021
Map released: 14/04/2021
Last modified: 02/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human immunodeficiency virus 1, Leiurus quinquestriatus hebraeus
Sample: Human immunodeficiency virus 1
Fitted models: 7lok

Deposition Authors: Jette CA , Bjorkman PJ
Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
Jette CA , Barnes CO, Kirk SM, Melillo B , Smith III AB, Bjorkman PJ
(2021) Nat Commun , 12 , 1950 - 1950
PUBMED: 33782388
DOI: doi:10.1038/s41467-021-21816-x
ISSN: 2041-1723