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EMD-23465

Single-particle
3.9 Å
EMD-23465
3D View Gallery
Deposition: 10/02/2021
Map released: 14/04/2021
Last modified: 02/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23465
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7lok summary report (pdf.gz) Map and 7lok FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of CD4 mimetic M48U1 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab

EMD-23465

Single-particle
3.9 Å
EMD-23465
3D View Gallery
Deposition: 10/02/2021
Map released: 14/04/2021
Last modified: 02/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human immunodeficiency virus 1, Leiurus quinquestriatus hebraeus
Sample: Human immunodeficiency virus 1
Fitted models: 7lok

Deposition Authors: Jette CA , Bjorkman PJ
Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
Jette CA , Barnes CO, Kirk SM, Melillo B , Smith III AB, Bjorkman PJ
(2021) Nat Commun , 12 , 1950 - 1950
PUBMED: 33782388
DOI: doi:10.1038/s41467-021-21816-x
ISSN: 2041-1723