Electron Microscopy Data Bank

EMD-23413

Single-particle
2.97 Å

3D View Gallery

Deposition: 03/02/2021
Map released: 03/03/2021
Last modified: 29/05/2024

Overview 3D View Sample Experiment Validation Additional data Links

EMD-23413

Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate (EM map was generated in Cryosparc with non-uniform refinement)

EMD-23413

Single-particle
2.97 Å
EMD-23413

3D View Gallery

Deposition: 03/02/2021
Map released: 03/03/2021
Last modified: 29/05/2024

Overview 3D View Sample Experiment Validation Additional data Links

Sample Organism: Homo sapiens
Sample: ACLY in complex with acetyl-CoA and oxaloacetate
Fitted models: 7lla

Deposition Authors: Wei X , Marmorstein R

Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.

Wei X , Marmorstein R
(2021) Nat Struct Mol Biol , 28 , 639 - 641

PUBMED: 34294921
DOI: doi:10.1038/s41594-021-00625-2
ISSN: 1545-9985

Secondary citations:

Wei X, Schultz K, Bazilevsky GA, Vogt A & Marmorstein R. (2020) Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat Struct Mol Biol, 27, 33 - 41

Grant Support:

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): P01 AG031862 (United States)

EMD-23413

EMD-23413

Archive Files (Depositor)

Validation (wwPDB)

EMDB Annotations

Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate (EM map was generated in Cryosparc with non-uniform refinement)

EMD-23413