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EMD-23390

Single-particle
3.0 Å
EMD-23390
3D View Gallery
Deposition: 28/01/2021
Map released: 03/03/2021
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23390
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7ljc summary report (pdf.gz) Map and 7ljc FULL report (pdf.gz)
EMICSS annotations (xml)

Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein

EMD-23390

Single-particle
3.0 Å
EMD-23390
3D View Gallery
Deposition: 28/01/2021
Map released: 03/03/2021
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Rattus norvegicus, Bos taurus, Lama glama
Sample: LY3154207 and SKF-81297-bound dopamine receptor 1 in complex with Gi protein
Fitted models: 7ljc

Deposition Authors: Zhuang Y, Krumm B
Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Zhuang Y, Krumm B, Zhang H, Zhou XE, Wang Y, Huang XP, Liu Y , Cheng X , Jiang Y, Jiang H , Zhang C , Yi W, Roth BL , Zhang Y , Xu HE
(2021) Cell Res , 31 , 593 - 596
PUBMED: 33750903
DOI: doi:10.1038/s41422-021-00482-0
ISSN: 1001-0602