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EMD-23294
Trimeric human Arginase 1 in complex with mAb5
EMD-23294
Single-particle3.05 Å
Deposition: 15/01/2021Map released: 01/09/2021
Last modified: 09/10/2024
Sample Organism:
Homo sapiens
Sample: Trimeric human arginase in complex with mAb5
Fitted models: 7ley
Deposition Authors: Gomez-Llorente Y, Scapin G
Sample: Trimeric human arginase in complex with mAb5
Fitted models: 7ley
Deposition Authors: Gomez-Llorente Y, Scapin G
Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action.
Palte RL 
,
Juan V,
Gomez-Llorente Y,
Bailly MA,
Chakravarthy K,
Chen X,
Cipriano D,
Fayadat-Dilman L,
Gathiaka S,
Greb H,
Hall B,
Handa M,
Hsieh M,
Kofman E,
Lin H,
Miller JR,
Nguyen N,
O'Neil J,
Shaheen H,
Sterner E,
Strickland C,
Sun A,
Taremi S,
Scapin G
(2021) Commun Biol , 4 , 927 - 927
,
Juan V,
Gomez-Llorente Y,
Bailly MA,
Chakravarthy K,
Chen X,
Cipriano D,
Fayadat-Dilman L,
Gathiaka S,
Greb H,
Hall B,
Handa M,
Hsieh M,
Kofman E,
Lin H,
Miller JR,
Nguyen N,
O'Neil J,
Shaheen H,
Sterner E,
Strickland C,
Sun A,
Taremi S,
Scapin G
(2021) Commun Biol , 4 , 927 - 927