EMD-23293

Single-particle
3.6 Å
EMD-23293
3D View Gallery
Deposition: 15/01/2021
Map released: 01/09/2021
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23293

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7lex summary report (pdf.gz) Map-7lex FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Trimeric human Arginase 1 in complex with mAb1 - 2 hArg:3 mAb1 complex

EMD-23293

Single-particle
3.6 Å
EMD-23293
3D View Gallery
Deposition: 15/01/2021
Map released: 01/09/2021
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Trimeric human arginase in complex with mAb1
Fitted models: 7lex

Deposition Authors: Gomez-Llorente Y , Scapin G
Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action.
Palte RL , Juan V, Gomez-Llorente Y , Bailly MA, Chakravarthy K, Chen X, Cipriano D, Fayadat-Dilman L, Gathiaka S, Greb H, Hall B, Handa M, Hsieh M, Kofman E, Lin H, Miller JR, Nguyen N, O'Neil J, Shaheen H, Sterner E, Strickland C, Sun A, Taremi S, Scapin G
(2021) Commun Biol , 4 , 927 - 927
PUBMED: 34326456
DOI: doi:10.1038/s42003-021-02444-z
ISSN: 2399-3642