Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-23149
Cryo-electron microscopy reconstruction of antibody DH898.1 Fab-dimer bound near the CD4 binding site of HIV Env SOSIP trimer CH848 10.17
EMD-23149
Single-particle4.7 Å
Deposition: 17/12/2020Map released: 03/03/2021
Last modified: 03/03/2021
Sample Organism:
Macaca mulatta,
Human immunodeficiency virus 1
Sample: Antibody DH898.1 Fab-dimer bound near the CD4 binding site of HIV Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 trimer
Deposition Authors: Edwards RJ, Acharya P
Sample: Antibody DH898.1 Fab-dimer bound near the CD4 binding site of HIV Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 trimer
Deposition Authors: Edwards RJ, Acharya P
Fab-dimerized glycan-reactive antibodies neutralize HIV and are prevalent in humans and rhesus macaques
Williams WB,
Meyerhoff RR,
Edwards RJ,
Li H,
Nicely NI,
Henderson R,
Zhou Y,
Janowska K,
Mansouri K,
Manne K,
Stalls V,
Hsu AL,
Borgnia MJ,
Stewart-Jones G,
Lee MS,
Bronkema N,
Perfect J,
Moody MA,
Wiehe K,
Bradley T,
Kepler TB,
Alam SM,
Foulger A,
Bonsignori M,
LaBranche CC,
Montefiori DC,
Seaman M,
Santra S,
Francica JR,
Lynn GM,
Aussedat B,
Walkowicz WE,
Laga R,
Kelso G,
Saunders KO,
Fera D,
Kwong PD,
Seder RA,
Bartesaghi A,
Shaw GM,
Acharya P,
Haynes BF
(2020) bioRxiv , https://doi.org/10.1101/2020.06.30.178921
(2020) bioRxiv , https://doi.org/10.1101/2020.06.30.178921