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EMD-23126
Cryo-EM structure of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein
EMD-23126
Single-particle2.97 Å
Deposition: 16/12/2020Map released: 24/03/2021
Last modified: 06/11/2024
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: Prefusion SARS-CoV-2 spike glycoprotein in complex with 4-18 Fab
Fitted models: 7l2e
Deposition Authors: Cerutti G
,
Shapiro L
Sample: Prefusion SARS-CoV-2 spike glycoprotein in complex with 4-18 Fab
Fitted models: 7l2e
Deposition Authors: Cerutti G
,
Shapiro L
Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite.
Cerutti G ,
Guo Y ,
Zhou T ,
Gorman J ,
Lee M ,
Rapp M ,
Reddem ER ,
Yu J,
Bahna F,
Bimela J,
Huang Y,
Katsamba PS ,
Liu L ,
Nair MS ,
Rawi R,
Olia AS,
Wang P ,
Zhang B,
Chuang GY,
Ho DD,
Sheng Z,
Kwong PD ,
Shapiro L
(2021) Cell Host Microbe , 29 , 819
,
Guo Y ,
Zhou T ,
Gorman J ,
Lee M ,
Rapp M ,
Reddem ER ,
Yu J,
Bahna F,
Bimela J,
Huang Y,
Katsamba PS ,
Liu L ,
Nair MS ,
Rawi R,
Olia AS,
Wang P ,
Zhang B,
Chuang GY,
Ho DD,
Sheng Z,
Kwong PD ,
Shapiro L
(2021) Cell Host Microbe , 29 , 819
Grant Support:
- Other private: Jack Ma Foundation (China)