EMD-23119

Single-particle
3.0 Å
EMD-23119
3D View Gallery
Deposition: 15/12/2020
Map released: 10/02/2021
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23119

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7l1v summary report (pdf.gz) Map-7l1v FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Orexin Receptor 2 (OX2R) in Complex with G Protein and Small-Molecule Agonist Compound 1

EMD-23119

Single-particle
3.0 Å
EMD-23119
3D View Gallery
Deposition: 15/12/2020
Map released: 10/02/2021
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus, Lama glama
Sample: Orexin Receptor 2 (OX2R) in Complex with G Protein and Small-Molecule Agonist Compound 1
Fitted models: 7l1v

Deposition Authors: Hong C , Byrne NJ
Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation.
Hong C , Byrne NJ , Zamlynny B, Tummala S , Xiao L , Shipman JM, Partridge AT , Minnick C , Breslin MJ, Rudd MT , Stachel SJ , Rada VL , Kern JC, Armacost KA, Hollingsworth SA , O'Brien JA, Hall DL, McDonald TP, Strickland C, Brooun A, Soisson SM , Hollenstein K
(2021) Nat Commun , 12 , 815 - 815
PUBMED: 33547286
DOI: doi:10.1038/s41467-021-21087-6
ISSN: 2041-1723