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EMD-23118
Orexin Receptor 2 (OX2R) in Complex with G Protein and Natural Peptide-Agonist Orexin B (OxB)
EMD-23118
Single-particle3.2 Å
Deposition: 15/12/2020Map released: 10/02/2021
Last modified: 20/11/2024
Sample Organism:
Homo sapiens,
Mus musculus
Sample: Orexin Receptor 2 (OX2R) in Complex with G Protein and Natural Peptide-Agonist Orexin B (OxB)
Fitted models: 7l1u
Deposition Authors: Hong C
,
Byrne NJ
Sample: Orexin Receptor 2 (OX2R) in Complex with G Protein and Natural Peptide-Agonist Orexin B (OxB)
Fitted models: 7l1u
Deposition Authors: Hong C
,
Byrne NJ
Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation.
Hong C ,
Byrne NJ ,
Zamlynny B,
Tummala S ,
Xiao L ,
Shipman JM,
Partridge AT ,
Minnick C ,
Breslin MJ,
Rudd MT ,
Stachel SJ ,
Rada VL ,
Kern JC,
Armacost KA,
Hollingsworth SA ,
O'Brien JA,
Hall DL,
McDonald TP,
Strickland C,
Brooun A,
Soisson SM ,
Hollenstein K
(2021) Nat Commun , 12 , 815 - 815
,
Byrne NJ ,
Zamlynny B,
Tummala S ,
Xiao L ,
Shipman JM,
Partridge AT ,
Minnick C ,
Breslin MJ,
Rudd MT ,
Stachel SJ ,
Rada VL ,
Kern JC,
Armacost KA,
Hollingsworth SA ,
O'Brien JA,
Hall DL,
McDonald TP,
Strickland C,
Brooun A,
Soisson SM ,
Hollenstein K
(2021) Nat Commun , 12 , 815 - 815