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EMD-23097
Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound domain-swapped antibody 2G12 from masked 3D refinement
EMD-23097
Single-particle3.1 Å
Deposition: 11/12/2020Map released: 30/12/2020
Last modified: 13/11/2024
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome-related coronavirus,
Severe acute respiratory syndrome coronavirus 2
Sample: Severe acute respiratory syndrome-related coronavirus spike glycoprotein in complex with domain-swapped antibody 2G12
Fitted models: 7l09
Deposition Authors: Manne K
,
Henderson R
Sample: Severe acute respiratory syndrome-related coronavirus spike glycoprotein in complex with domain-swapped antibody 2G12
Fitted models: 7l09
Deposition Authors: Manne K
,
Henderson R
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Williams WB,
Meyerhoff RR
,
Edwards RJ
,
Li H,
Manne K
,
Nicely NI
,
Henderson R,
Zhou Y
,
Janowska K,
Mansouri K
,
Gobeil S
,
Evangelous T,
Hora B,
Berry M,
Abuahmad AY,
Sprenz J,
Deyton M,
Stalls V
,
Kopp M,
Hsu AL,
Borgnia MJ,
Stewart-Jones GBE,
Lee MS,
Bronkema N,
Moody MA,
Wiehe K,
Bradley T,
Alam SM,
Parks RJ,
Foulger A,
Oguin T,
Sempowski GD
,
Bonsignori M,
LaBranche CC,
Montefiori DC,
Seaman M,
Santra S,
Perfect J,
Francica JR,
Lynn GM,
Aussedat B,
Walkowicz WE,
Laga R,
Kelsoe G,
Saunders KO,
Fera D,
Kwong PD
,
Seder RA,
Bartesaghi A,
Shaw GM,
Acharya P
,
Haynes BF
(2021) Cell , 184 , 2955
,
Edwards RJ
,
Li H,
Manne K
,
Nicely NI
,
Henderson R,
Zhou Y
,
Janowska K,
Mansouri K
,
Gobeil S
,
Evangelous T,
Hora B,
Berry M,
Abuahmad AY,
Sprenz J,
Deyton M,
Stalls V
,
Kopp M,
Hsu AL,
Borgnia MJ,
Stewart-Jones GBE,
Lee MS,
Bronkema N,
Moody MA,
Wiehe K,
Bradley T,
Alam SM,
Parks RJ,
Foulger A,
Oguin T,
Sempowski GD
,
Bonsignori M,
LaBranche CC,
Montefiori DC,
Seaman M,
Santra S,
Perfect J,
Francica JR,
Lynn GM,
Aussedat B,
Walkowicz WE,
Laga R,
Kelsoe G,
Saunders KO,
Fera D,
Kwong PD
,
Seder RA,
Bartesaghi A,
Shaw GM,
Acharya P
,
Haynes BF
(2021) Cell , 184 , 2955
Grant Support:
