EMD-23060
The stress-sensing domain of activated IRE1a forms helical filaments in narrow ER membrane tubes
EMD-23060
Subtomogram averaging30.0 Å
Deposition: 02/12/2020Map released: 10/11/2021
Last modified: 08/06/2022
Sample Organism:
Homo sapiens
Sample: Double-helical arrangement of human IRE1a luminal domain in 30 nm ER tubes
Deposition Authors: Carter SD
,
Tran NH ,
De Maziere A ,
Ashkenazi A ,
Klumpermann J,
Walter P ,
Jensen GJ
Sample: Double-helical arrangement of human IRE1a luminal domain in 30 nm ER tubes
Deposition Authors: Carter SD
,
Tran NH ,
De Maziere A ,
Ashkenazi A ,
Klumpermann J,
Walter P ,
Jensen GJ
The stress-sensing domain of activated IRE1 alpha forms helical filaments in narrow ER membrane tubes.
Tran NH ,
Carter SD ,
De Maziere A ,
Ashkenazi A ,
Klumperman J ,
Walter P ,
Jensen GJ
(2021) Science , 374 , 52 - 57
,
Carter SD ,
De Maziere A ,
Ashkenazi A ,
Klumperman J ,
Walter P ,
Jensen GJ
(2021) Science , 374 , 52 - 57
Grant Support:
- National Institutes of Health/National Center for Research Resources (NIH/NCRR): P50 AI150464 (United States)
- National Institutes of Health/National Center for Research Resources (NIH/NCRR): R35 GM122588 (United States)
- National Institutes of Health/National Center for Research Resources (NIH/NCRR): R01-GM032384 (United States)