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EMD-23035

Single-particle
3.4 Å
EMD-23035 Deposition: 24/11/2020
Map released: 17/03/2021
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23035

Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048. Cluster identified by 3-dimensional variability analysis in cryoSPARC.

EMD-23035

Single-particle
3.4 Å
EMD-23035 Deposition: 24/11/2020
Map released: 17/03/2021
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rous sarcoma virus (strain Schmidt-Ruppin A)
Sample: Cleaved synaptic complex (CSC) formed with Rous sarcoma virus integrase and viral DNA in presence of HIV-1 integrase strand inhibitor MK-2048
Fitted models: 7ku7

Deposition Authors: Pandey KK , Bera S
Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome.
Pandey KK , Bera S, Shi K , Rau MJ , Oleru AV, Fitzpatrick JAJ , Engelman AN , Aihara H , Grandgenett DP
(2021) Commun Biol , 4 , 330 - 330
PUBMED: 33712691
DOI: doi:10.1038/s42003-021-01855-2
ISSN: 2399-3642