Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-22980

Single-particle
3.6 Å
EMD-22980
3D View Gallery
Deposition: 09/11/2020
Map released: 17/03/2021
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22980
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7koq summary report (pdf.gz) Map and 7koq FULL report (pdf.gz)
EMICSS annotations (xml)

Alpha-7 nicotinic acetylcholine receptor bound to epibatidine in a desensitized state

EMD-22980

Single-particle
3.6 Å
EMD-22980
3D View Gallery
Deposition: 09/11/2020
Map released: 17/03/2021
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: alpha 7 nicotinic receptor in complex with the agonist epibatidine
Fitted models: 7koq

Deposition Authors: Noviello CM , Hibbs RE
Structure and gating mechanism of the alpha 7 nicotinic acetylcholine receptor.
Noviello CM , Gharpure A, Mukhtasimova N, Cabuco R, Baxter L, Borek D , Sine SM, Hibbs RE
(2021) Cell , 184 , 2121
PUBMED: 33735609
DOI: doi:10.1016/j.cell.2021.02.049
ISSN: 1097-4172