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EMD-22922

Single-particle
3.39 Å
EMD-22922
3D View Gallery
Deposition: 02/11/2020
Map released: 09/12/2020
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22922
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7kmb summary report (pdf.gz) Map and 7kmb FULL report (pdf.gz)
EMICSS annotations (xml)

ACE2-RBD Focused Refinement Using Symmetry Expansion of Applied C3 for Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 7.4

EMD-22922

Single-particle
3.39 Å
EMD-22922
3D View Gallery
Deposition: 02/11/2020
Map released: 09/12/2020
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: ACE2-RBD pH 7.4
Fitted models: 7kmb

Deposition Authors: Gorman J , Kwong PD
Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Zhou T , Tsybovsky Y, Gorman J , Rapp M, Cerutti G , Chuang GY, Katsamba PS , Sampson JM , Schon A, Bimela J, Boyington JC, Nazzari A , Olia AS, Shi W, Sastry M, Stephens T, Stuckey J, Teng IT, Wang P, Wang S, Zhang B, Friesner RA, Ho DD, Mascola JR, Shapiro L, Kwong PD
(2020) Cell Host Microbe , 28 , 867 - 879.e5
PUBMED: 33271067
DOI: doi:10.1016/j.chom.2020.11.004
ISSN: 1934-6069