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EMD-22916
Structure of the SARS-CoV-2 S 6P trimer in complex with the ACE2 protein decoy, CTC-445.2 (State 4)
EMD-22916
Single-particle4.1 Å
Deposition: 29/10/2020Map released: 11/11/2020
Last modified: 04/06/2025
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: Ternary complex of CTC445.2 inhibitor with SARS-CoV-2 S 6P glycoprotin
Fitted models: 7kl9
Deposition Authors: Barnes CO
,
Bjorkman PJ
Sample: Ternary complex of CTC445.2 inhibitor with SARS-CoV-2 S 6P glycoprotin
Fitted models: 7kl9
Deposition Authors: Barnes CO
,
Bjorkman PJ
De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2.
Linsky TW ,
Vergara R ,
Codina N ,
Nelson JW ,
Walker MJ ,
Su W ,
Barnes CO ,
Hsiang TY ,
Esser-Nobis K ,
Yu K ,
Reneer ZB ,
Hou YJ ,
Priya T,
Mitsumoto M ,
Pong A,
Lau UY ,
Mason ML ,
Chen J ,
Chen A,
Berrocal T ,
Peng H,
Clairmont NS,
Castellanos J,
Lin YR,
Josephson-Day A ,
Baric RS ,
Fuller DH ,
Walkey CD,
Ross TM,
Swanson R ,
Bjorkman PJ ,
Gale Jr M ,
Blancas-Mejia LM ,
Yen HL ,
Silva DA
(2020) Science , 370 , 1208 - 1214
,
Vergara R ,
Codina N ,
Nelson JW ,
Walker MJ ,
Su W ,
Barnes CO ,
Hsiang TY ,
Esser-Nobis K ,
Yu K ,
Reneer ZB ,
Hou YJ ,
Priya T,
Mitsumoto M ,
Pong A,
Lau UY ,
Mason ML ,
Chen J ,
Chen A,
Berrocal T ,
Peng H,
Clairmont NS,
Castellanos J,
Lin YR,
Josephson-Day A ,
Baric RS ,
Fuller DH ,
Walkey CD,
Ross TM,
Swanson R ,
Bjorkman PJ ,
Gale Jr M ,
Blancas-Mejia LM ,
Yen HL ,
Silva DA
(2020) Science , 370 , 1208 - 1214
Grant Support: