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EMD-22879
cryoEM structure of LILRB1 D3D4 domain-inserted antibody MDB1 Fab in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain
EMD-22879
Single-particle3.54 Å
Deposition: 21/10/2020Map released: 31/03/2021
Last modified: 16/10/2024
Sample Organism:
Homo sapiens,
Plasmodium falciparum (isolate 3D7)
Sample: MDB1 Fab
Fitted models: 7khf
Deposition Authors: Xu K, Kwong PD
Sample: MDB1 Fab
Fitted models: 7khf
Deposition Authors: Xu K, Kwong PD
Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
Chen Y ,
Xu K,
Piccoli L ,
Foglierini M ,
Tan J ,
Jin W,
Gorman J ,
Tsybovsky Y,
Zhang B,
Traore B,
Silacci-Fregni C,
Daubenberger C ,
Crompton PD,
Geiger R ,
Sallusto F ,
Kwong PD ,
Lanzavecchia A
(2021) Nature , 592 , 639 - 643
,
Xu K,
Piccoli L ,
Foglierini M ,
Tan J ,
Jin W,
Gorman J ,
Tsybovsky Y,
Zhang B,
Traore B,
Silacci-Fregni C,
Daubenberger C ,
Crompton PD,
Geiger R ,
Sallusto F ,
Kwong PD ,
Lanzavecchia A
(2021) Nature , 592 , 639 - 643
Grant Support:
- Other private: Simons Foundation SF349247 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): U24 GM129539 (United States)