Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-22692

Single-particle
3.1 Å
EMD-22692
3D View Gallery
Deposition: 21/09/2020
Map released: 10/02/2021
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22692
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7k6q summary report (pdf.gz) Map and 7k6q FULL report (pdf.gz)
EMICSS annotations (xml)

Active state Dot1 bound to the H4K16ac nucleosome

EMD-22692

Single-particle
3.1 Å
EMD-22692
3D View Gallery
Deposition: 21/09/2020
Map released: 10/02/2021
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Xenopus laevis, Saccharomyces cerevisiae, synthetic construct, Homo sapiens
Sample: Active state Dot1 bound to the H4K16ac nucleosome
Fitted models: 7k6q

Deposition Authors: Valencia-Sanchez MI , De Ioannes PE
Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
Valencia-Sanchez MI , De Ioannes P , Wang M , Truong DM , Lee R , Armache JP, Boeke JD , Armache KJ
(2021) Science , 371
PUBMED: 33479126
DOI: doi:10.1126/science.abc6663
ISSN: 1095-9203
ASTM: SCIEAS