Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-22660
SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)
EMD-22660
Single-particle3.7 Å
Deposition: 14/09/2020Map released: 07/10/2020
Last modified: 30/10/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment
Fitted models: 7k45
Deposition Authors: Tortorici MA
,
Veesler D ,
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Sample: SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment
Fitted models: 7k45
Deposition Authors: Tortorici MA
,
Veesler D ,
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Tortorici MA ,
Beltramello M ,
Lempp FA,
Pinto D,
Dang HV ,
Rosen LE ,
McCallum M ,
Bowen J,
Minola A,
Jaconi S,
Zatta F ,
De Marco A ,
Guarino B ,
Bianchi S ,
Lauron EJ,
Tucker H ,
Zhou J ,
Peter A ,
Havenar-Daughton C ,
Wojcechowskyj JA ,
Case JB ,
Chen RE,
Kaiser H ,
Montiel-Ruiz M ,
Meury M ,
Czudnochowski N ,
Spreafico R ,
Dillen J ,
Ng C ,
Sprugasci N ,
Culap K ,
Benigni F ,
Abdelnabi R ,
Foo SC ,
Schmid MA ,
Cameroni E ,
Riva A ,
Gabrieli A ,
Galli M ,
Pizzuto MS ,
Neyts J ,
Diamond MS ,
Virgin HW ,
Snell G,
Corti D ,
Fink K,
Veesler D
(2020) Science , 370 , 950 - 957
,
Beltramello M ,
Lempp FA,
Pinto D,
Dang HV ,
Rosen LE ,
McCallum M ,
Bowen J,
Minola A,
Jaconi S,
Zatta F ,
De Marco A ,
Guarino B ,
Bianchi S ,
Lauron EJ,
Tucker H ,
Zhou J ,
Peter A ,
Havenar-Daughton C ,
Wojcechowskyj JA ,
Case JB ,
Chen RE,
Kaiser H ,
Montiel-Ruiz M ,
Meury M ,
Czudnochowski N ,
Spreafico R ,
Dillen J ,
Ng C ,
Sprugasci N ,
Culap K ,
Benigni F ,
Abdelnabi R ,
Foo SC ,
Schmid MA ,
Cameroni E ,
Riva A ,
Gabrieli A ,
Galli M ,
Pizzuto MS ,
Neyts J ,
Diamond MS ,
Virgin HW ,
Snell G,
Corti D ,
Fink K,
Veesler D
(2020) Science , 370 , 950 - 957