EMD-22453

Single-particle
5.2 Å
EMD-22453
3D View Gallery
Deposition: 14/08/2020
Map released: 09/12/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22453

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7jsg summary report (pdf.gz) Map-7jsg FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Adeno-Associated Virus 2 Rep68 HD Hexamer-ssDNA with ATPgS

EMD-22453

Single-particle
5.2 Å
EMD-22453
3D View Gallery
Deposition: 14/08/2020
Map released: 09/12/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Adeno-associated virus - 2, synthetic construct
Sample: Rep68 Helicase in complex with ssDNA (poly-dT)
Fitted models: 7jsg

Deposition Authors: Escalante CR
The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Santosh V, Musayev FN, Jaiswal R, Zarate-Perez F , Vandewinkel B , Dierckx C, Endicott M , Sharifi K, Dryden K, Henckaerts E , Escalante CR
(2020) Nucleic Acids Res , 48 , 12983 - 12999
PUBMED: 33270897
DOI: doi:10.1093/nar/gkaa1133
ISSN: 1362-4962
ASTM: NARHAD