EMD-22452

Single-particle
6.7 Å
EMD-22452
3D View Gallery
Deposition: 14/08/2020
Map released: 16/12/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22452

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7jsf summary report (pdf.gz) Map-7jsf FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Adeno-Associated Virus Helicase domain Heptamer with ssDNA

EMD-22452

Single-particle
6.7 Å
EMD-22452
3D View Gallery
Deposition: 14/08/2020
Map released: 16/12/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Adeno-associated virus - 2, synthetic construct
Sample: Helicase domain heptamer of Rep68 complx bound to ssDNA
Fitted models: 7jsf

Deposition Authors: Escalante CR
The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Santosh V, Musayev FN, Jaiswal R, Zarate-Perez F , Vandewinkel B , Dierckx C, Endicott M , Sharifi K, Dryden K, Henckaerts E , Escalante CR
(2020) Nucleic Acids Res , 48 , 12983 - 12999
PUBMED: 33270897
DOI: doi:10.1093/nar/gkaa1133
ISSN: 1362-4962
ASTM: NARHAD