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EMD-22302
Cryo-EM structure of vaccine-elicited Rhesus VH6-1 antibody 789-203-3C12 in complex with stabilized SI06 (A/Solomon Islands/3/06) Influenza Hemagglutinin Trimer
EMD-22302
Single-particle3.85 Å
Deposition: 15/07/2020Map released: 21/07/2021
Last modified: 16/10/2024
Sample Organism:
Macaca mulatta,
Influenza A virus (A/Solomon Islands/3/2006(H1N1))
Sample: Influenza Hemagglutinin SI06 Trimer in complex with 789-203-3C12 Fab
Fitted models: 6xsk
Deposition Authors: Cerutti G
,
Gorman J
Sample: Influenza Hemagglutinin SI06 Trimer in complex with 789-203-3C12 Fab
Fitted models: 6xsk
Deposition Authors: Cerutti G
,
Gorman J
Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.
Moin SM,
Boyington JC,
Boyoglu-Barnum S,
Gillespie RA,
Cerutti G ,
Cheung CS,
Cagigi A,
Gallagher JR,
Brand J ,
Prabhakaran M,
Tsybovsky Y,
Stephens T,
Fisher BE,
Creanga A,
Ataca S,
Rawi R,
Corbett KS,
Crank MC,
Karlsson Hedestam GB,
Gorman J ,
McDermott AB,
Harris AK ,
Zhou T,
Kwong PD ,
Shapiro L,
Mascola JR,
Graham BS,
Kanekiyo M
(2022) Immunity , 55 , 2405 - 2418.e7
,
Cheung CS,
Cagigi A,
Gallagher JR,
Brand J ,
Prabhakaran M,
Tsybovsky Y,
Stephens T,
Fisher BE,
Creanga A,
Ataca S,
Rawi R,
Corbett KS,
Crank MC,
Karlsson Hedestam GB,
Gorman J ,
McDermott AB,
Harris AK ,
Zhou T,
Kwong PD ,
Shapiro L,
Mascola JR,
Graham BS,
Kanekiyo M
(2022) Immunity , 55 , 2405 - 2418.e7
Grant Support:
- Bill & Melinda Gates Foundation: (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): (United States)