EMD-22220

Helical reconstruction
3.72 Å
EMD-22220
3D View Gallery
Deposition: 26/06/2020
Map released: 25/11/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-22220

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6xkk summary report (pdf.gz) Map-6xkk FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of the NLRP1-CARD filament

EMD-22220

Helical reconstruction
3.72 Å
EMD-22220
3D View Gallery
Deposition: 26/06/2020
Map released: 25/11/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NLRP1-CARD filament
Fitted models: 6xkk

Deposition Authors: Hollingsworth LR , David L
Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
Robert Hollingsworth L, David L, Li Y, Griswold AR , Ruan J, Sharif H, Fontana P , Orth-He EL , Fu TM , Bachovchin DA , Wu H
(2021) Nat Commun , 12 , 189 - 189
PUBMED: 33420033
DOI: doi:10.1038/s41467-020-20320-y
ISSN: 2041-1723