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EMD-22074
Cryo-EM structure of NLRP1-DPP9 complex
EMD-22074
Single-particle3.6 Å
Deposition: 27/05/2020Map released: 10/03/2021
Last modified: 21/05/2025
Sample Organism:
Homo sapiens
Sample: DPP9-NLRP1 complex
Fitted models: 6x6a
Deposition Authors: Hollingsworth LR
,
Sharif H ,
Griswold AR ,
Fontana P,
Mintseris J,
Dagbay KB ,
Paulo JA ,
Gygi SP ,
Bachovchin DA ,
Wu H
Sample: DPP9-NLRP1 complex
Fitted models: 6x6a
Deposition Authors: Hollingsworth LR
,
Sharif H ,
Griswold AR ,
Fontana P,
Mintseris J,
Dagbay KB ,
Paulo JA ,
Gygi SP ,
Bachovchin DA ,
Wu H
DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.
Hollingsworth LR ,
Sharif H ,
Griswold AR ,
Fontana P,
Mintseris J,
Dagbay KB ,
Paulo JA ,
Gygi SP ,
Bachovchin DA ,
Wu H
(2021) Nature , 592 , 778 - 783
,
Sharif H ,
Griswold AR ,
Fontana P,
Mintseris J,
Dagbay KB ,
Paulo JA ,
Gygi SP ,
Bachovchin DA ,
Wu H
(2021) Nature , 592 , 778 - 783
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