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EMD-21994
Non peptide agonist PF-06882961, bound to Glucagon-Like peptide-1 (GLP-1) Receptor
EMD-21994
Single-particle2.5 Å
Deposition: 18/05/2020Map released: 09/09/2020
Last modified: 28/05/2025
Sample Organism:
Homo sapiens,
Lama glama
Sample: PF-06882961:GLP-1R:Gs Complex
Fitted models: 6x1a
Deposition Authors: Belousoff MJ
,
Zhang X
Sample: PF-06882961:GLP-1R:Gs Complex
Fitted models: 6x1a
Deposition Authors: Belousoff MJ
,
Zhang X
Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists.
Zhang X ,
Belousoff MJ ,
Zhao P,
Kooistra AJ ,
Truong TT,
Ang SY ,
Underwood CR,
Egebjerg T,
Senel P,
Stewart GD ,
Liang YL,
Glukhova A ,
Venugopal H,
Christopoulos A,
Furness SGB ,
Miller LJ,
Reedtz-Runge S,
Langmead CJ ,
Gloriam DE ,
Danev R,
Sexton PM,
Wootten D
(2020) Mol Cell , 80 , 485
,
Belousoff MJ ,
Zhao P,
Kooistra AJ ,
Truong TT,
Ang SY ,
Underwood CR,
Egebjerg T,
Senel P,
Stewart GD ,
Liang YL,
Glukhova A ,
Venugopal H,
Christopoulos A,
Furness SGB ,
Miller LJ,
Reedtz-Runge S,
Langmead CJ ,
Gloriam DE ,
Danev R,
Sexton PM,
Wootten D
(2020) Mol Cell , 80 , 485
Grant Support:
- National Health and Medical Research Council (NHMRC, Australia): 1061044 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1065410 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1120919 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1126857 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 1055134 (Australia)