Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-21969

Single-particle
2.75 Å
EMD-21969
3D View Gallery
Deposition: 13/05/2020
Map released: 17/06/2020
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21969
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6wyv summary report (pdf.gz) Map and 6wyv FULL report (pdf.gz)
EMICSS annotations (xml)

E. coli 50S ribosome bound to compounds 47 and VS1

EMD-21969

Single-particle
2.75 Å
EMD-21969
3D View Gallery
Deposition: 13/05/2020
Map released: 17/06/2020
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli, Streptomyces virginiae
Sample: 50S E. coli ribosome
Fitted models: 6wyv

Deposition Authors: Pellegrino J , Lee DJ
Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Li Q , Pellegrino J , Lee DJ , Tran AA, Chaires HA , Wang R , Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT, van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray B, Jacobson MP , Muhle E , Chesneau O, Fraser JS , Seiple IB
(2020) Nature , 586 , 145 - 150
PUBMED: 32968273
DOI: doi:10.1038/s41586-020-2761-3
ISSN: 1476-4687
ASTM: NATUAS