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EMD-21861

Single-particle
3.27 Å
EMD-21861
3D View Gallery
Deposition: 25/04/2020
Map released: 05/08/2020
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21861
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6wou summary report (pdf.gz) Map and 6wou FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with FKBP12.6 in nanodisc

EMD-21861

Single-particle
3.27 Å
EMD-21861
3D View Gallery
Deposition: 25/04/2020
Map released: 05/08/2020
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: recombinant mouse Ryanodine Receptor type 2, RyR2, with mutation R176Q in complex with FKBP12.6
Fitted models: 6wou

Deposition Authors: Iyer KA , Hu Y, Kurebayashi N, Murayama T , Samso M
Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Iyer KA , Hu Y, Nayak AR , Kurebayashi N, Murayama T , Samso M
(2020) Sci Adv , 6 , eabb2964 - eabb2964
PUBMED: 32832689
DOI: doi:10.1126/sciadv.abb2964
ISSN: 2375-2548