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EMD-21705

Single-particle
3.46 Å
EMD-21705
3D View Gallery
Deposition: 16/04/2020
Map released: 21/04/2021
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21705
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6wkn summary report (pdf.gz) Map and 6wkn FULL report (pdf.gz)
EMICSS annotations (xml)

PL-bound rat TRPV2 in nanodiscs

EMD-21705

Single-particle
3.46 Å
EMD-21705
3D View Gallery
Deposition: 16/04/2020
Map released: 21/04/2021
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: Homotetramer of full-length rat TRPV2 bound to piperlongumine
Fitted models: 6wkn

Deposition Authors: Pumroy RP, Moiseenkova-Bell VY
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.
Conde J , Pumroy RA, Baker C, Rodrigues T , Guerreiro A , Sousa BB , Marques MC, de Almeida BP, Lee S , Leites EP , Picard D, Samanta A, Vaz SH , Sieglitz F, Langini M , Remke M, Roque R, Weiss T , Weller M , Liu Y, Han S, Corzana F , Morais VA , Faria CC , Carvalho T , Filippakopoulos P , Snijder B , Barbosa-Morais NL , Moiseenkova-Bell VY, Bernardes GJL
(2021) ACS Cent Sci , 7 , 868 - 881
PUBMED: 34079902
DOI: doi:10.1021/acscentsci.1c00070
ISSN: 2374-7951