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EMD-21692

Single-particle
7.5 Å
EMD-21692
3D View Gallery
Deposition: 13/04/2020
Map released: 02/12/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21692
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6wjf summary report (pdf.gz) Map and 6wjf FULL report (pdf.gz)
EMICSS annotations (xml)

PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma

EMD-21692

Single-particle
7.5 Å
EMD-21692
3D View Gallery
Deposition: 13/04/2020
Map released: 02/12/2020
Last modified: 06/03/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Rattus norvegicus
Sample: PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
Fitted models: 6wjf

Deposition Authors: Lu T-W, Aoto PC
Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Lu TW, Aoto PC , Weng JH , Nielsen C , Cash JN , Hall J , Zhang P , Simon SM , Cianfrocco MA , Taylor SS
(2020) PLoS Biol , 18 , e3001018 - e3001018
PUBMED: 33370777
DOI: doi:10.1371/journal.pbio.3001018
ISSN: 1545-7885