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EMD-21685
Structure of human GABA(B) receptor in an inactive state
EMD-21685
Single-particle3.3 Å
Deposition: 10/04/2020Map released: 01/07/2020
Last modified: 09/10/2024
Sample Organism:
Homo sapiens
Sample: Heterodimer human GABA(B) receptor composed of GABA(B1b) and GABA(B2) subunits.
Fitted models: 6wiv
Deposition Authors: Park J, Fu Z
,
Frangaj A ,
Liu J,
Mosyak L,
Shen T,
Slavkovich VN,
Ray KM,
Taura J,
Cao B,
Geng Y,
Zuo H ,
Kou Y,
Grassucci R,
Chen S ,
Liu Z,
Lin X,
Williams JP ,
Rice WJ ,
Eng ET ,
Huang RK,
Soni RK,
Kloss B ,
Yu Z,
Javitch JA,
Hendrickson WA,
Slesinger PA ,
Quick M,
Graziano J,
Yu H ,
Fiehn O ,
Clarke OB ,
Frank J ,
Fan QR
Sample: Heterodimer human GABA(B) receptor composed of GABA(B1b) and GABA(B2) subunits.
Fitted models: 6wiv
Deposition Authors: Park J, Fu Z
,
Frangaj A ,
Liu J,
Mosyak L,
Shen T,
Slavkovich VN,
Ray KM,
Taura J,
Cao B,
Geng Y,
Zuo H ,
Kou Y,
Grassucci R,
Chen S ,
Liu Z,
Lin X,
Williams JP ,
Rice WJ ,
Eng ET ,
Huang RK,
Soni RK,
Kloss B ,
Yu Z,
Javitch JA,
Hendrickson WA,
Slesinger PA ,
Quick M,
Graziano J,
Yu H ,
Fiehn O ,
Clarke OB ,
Frank J ,
Fan QR
Structure of human GABABreceptor in an inactive state.
Park J,
Fu Z ,
Frangaj A ,
Liu J,
Mosyak L,
Shen T,
Slavkovich VN,
Ray KM,
Taura J,
Cao B,
Geng Y,
Zuo H ,
Kou Y,
Grassucci R,
Chen S ,
Liu Z,
Lin X,
Williams JP ,
Rice WJ ,
Eng ET ,
Huang RK,
Soni RK,
Kloss B ,
Yu Z,
Javitch JA,
Hendrickson WA,
Slesinger PA ,
Quick M,
Graziano J,
Yu H ,
Fiehn O ,
Clarke OB ,
Frank J ,
Fan QR
(2020) Nature , 584 , 304 - 309
,
Frangaj A ,
Liu J,
Mosyak L,
Shen T,
Slavkovich VN,
Ray KM,
Taura J,
Cao B,
Geng Y,
Zuo H ,
Kou Y,
Grassucci R,
Chen S ,
Liu Z,
Lin X,
Williams JP ,
Rice WJ ,
Eng ET ,
Huang RK,
Soni RK,
Kloss B ,
Yu Z,
Javitch JA,
Hendrickson WA,
Slesinger PA ,
Quick M,
Graziano J,
Yu H ,
Fiehn O ,
Clarke OB ,
Frank J ,
Fan QR
(2020) Nature , 584 , 304 - 309
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM088454 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM125801 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): U2CES030158 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): P41GM116799 (United States)
- National Institutes of Health/Office of the Director: R01GM107462 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): P41GM103310 (United States)