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EMD-21543

Single-particle
4.6 Å
EMD-21543
3D View Gallery
Deposition: 13/03/2020
Map released: 31/03/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21543
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6w5m summary report (pdf.gz) Map and 6w5m FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02)

EMD-21543

Single-particle
4.6 Å
EMD-21543
3D View Gallery
Deposition: 13/03/2020
Map released: 31/03/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Xenopus laevis, synthetic construct
Sample: MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome
Fitted models: 6w5m

Deposition Authors: Park SH, Lee YT
Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Lee YT , Ayoub A, Park SH, Sha L , Xu J, Mao F , Zheng W , Zhang Y , Cho US, Dou Y
(2021) Nat Commun , 12 , 2953 - 2953
PUBMED: 34012049
DOI: doi:10.1038/s41467-021-23268-9
ISSN: 2041-1723