EMD-21438

Single-particle
3.7 Å
EMD-21438
3D View Gallery
Deposition: 21/02/2020
Map released: 13/05/2020
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21438

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6vxi summary report (pdf.gz) Map-6vxi FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of ABCG2 bound to mitoxantrone

EMD-21438

Single-particle
3.7 Å
EMD-21438
3D View Gallery
Deposition: 21/02/2020
Map released: 13/05/2020
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: ABCG2 reconstituted in lipid nanodisc
Fitted models: 6vxi

Deposition Authors: Orlando BJ, Liao M
ABCG2 transports anticancer drugs via a closed-to-open switch.
Orlando BJ, Liao M
(2020) Nat Commun , 11 , 2264 - 2264
PUBMED: 32385283
DOI: doi:10.1038/s41467-020-16155-2
ISSN: 2041-1723
Grant Support: