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EMD-21415

Single-particle
3.21 Å
EMD-21415 Deposition: 19/02/2020
Map released: 13/05/2020
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21415

Head region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.

EMD-21415

Single-particle
3.21 Å
EMD-21415 Deposition: 19/02/2020
Map released: 13/05/2020
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sample: Head region of the open-leg conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Fitted models: 6vwg

Deposition Authors: Xu Y, Kirk NS
How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor.
Xu Y, Kirk NS , Venugopal H , Margetts MB, Croll TI , Sandow JJ, Webb AI , Delaine CA, Forbes BE , Lawrence MC
(2020) Structure , 28 , 786 - 798.e6
PUBMED: 32459985
DOI: doi:10.1016/j.str.2020.05.002
ISSN: 0969-2126
ASTM: STRUE6