EMD-21408

Single-particle
3.72 Å
EMD-21408
3D View Gallery
Deposition: 18/02/2020
Map released: 21/10/2020
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21408
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6vvz summary report (pdf.gz) Map and 6vvz FULL report (pdf.gz)
EMICSS annotations (xml)

Mycobacterium tuberculosis RNAP S456L mutant transcription initiation intermediate structure with Sorangicin

EMD-21408

Single-particle
3.72 Å
EMD-21408
3D View Gallery
Deposition: 18/02/2020
Map released: 21/10/2020
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycobacterium tuberculosis
Sample: Mycobacterium tuberculosis RNAP S456L mutant promoter melting intermediate complex
Fitted models: 6vvz

Deposition Authors: Lilic M , Boyaci H
The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Lilic M , Chen J , Boyaci H, Braffman N , Hubin EA, Herrmann J, Muller R , Mooney R, Landick R , Darst SA , Campbell EA
(2020) PNAS , 117 , 30423 - 30432
PUBMED: 33199626
DOI: doi:10.1073/pnas.2013706117
ISSN: 1091-6490
ASTM: PNASA6