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EMD-21406

Single-particle
3.39 Å
EMD-21406
3D View Gallery
Deposition: 18/02/2020
Map released: 21/10/2020
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21406
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6vvx summary report (pdf.gz) Map and 6vvx FULL report (pdf.gz)
EMICSS annotations (xml)

Mycobacterium tuberculosis WT RNAP transcription initiation intermediate structure with Sorangicin

EMD-21406

Single-particle
3.39 Å
EMD-21406
3D View Gallery
Deposition: 18/02/2020
Map released: 21/10/2020
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycobacterium tuberculosis
Sample: Mycobacterium tuberculosis RNAP promoter open complex
Fitted models: 6vvx

Deposition Authors: Lilic M , Boyaci H
The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Lilic M , Chen J , Boyaci H, Braffman N , Hubin EA, Herrmann J, Muller R , Mooney R, Landick R , Darst SA , Campbell EA
(2020) PNAS , 117 , 30423 - 30432
PUBMED: 33199626
DOI: doi:10.1073/pnas.2013706117
ISSN: 1091-6490
ASTM: PNASA6