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EMD-21311

Single-particle
9.0 Å
EMD-21311
3D View Gallery
Deposition: 03/02/2020
Map released: 26/08/2020
Last modified: 23/12/2020
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21311
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Cryo-EM map of C-terminal half of Leucine Rich Repeat Kinase 2 as a COR-COR domain dimer in the presence of the MLi-2 kinase inhibitor at 9.0 angstroms

EMD-21311

Single-particle
9.0 Å
EMD-21311
3D View Gallery
Deposition: 03/02/2020
Map released: 26/08/2020
Last modified: 23/12/2020
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Truncated Leucine Rich Repeat Kinase 2 as a COR-COR domain mediated dimer in the presence of the MLi-2 kinase inhibitor.

Deposition Authors: Leschziner A, Deniston C, Lahiri I
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Deniston CK, Salogiannis J , Mathea S , Snead DM , Lahiri I, Matyszewski M , Donosa O , Watanabe R , Bohning J , Shiau AK, Knapp S , Villa E , Reck-Peterson SL , Leschziner AE
(2020) Nature , 588 , 344 - 349
PUBMED: 32814344
DOI: doi:10.1038/s41586-020-2673-2
ISSN: 1476-4687
ASTM: NATUAS