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EMD-21247
A 2.8 Angstrom Cryo-EM Structure of a Glycoprotein B-Neutralizing Antibody Complex Reveals a Critical Domain for Herpesvirus Fusion Initiation
EMD-21247
Single-particle2.8 Å
Deposition: 29/01/2020Map released: 15/07/2020
Last modified: 28/05/2025
Sample Organism:
Homo sapiens,
Human alphaherpesvirus 3
Sample: Varicella zoster virus glycoprotein B in complex with Fab fragments derived from human monoclonal antibody 93k
Fitted models: 6vn1
Deposition Authors: Oliver SL
Sample: Varicella zoster virus glycoprotein B in complex with Fab fragments derived from human monoclonal antibody 93k
Fitted models: 6vn1
Deposition Authors: Oliver SL
A glycoprotein B-neutralizing antibody structure at 2.8 angstrom uncovers a critical domain for herpesvirus fusion initiation.
Oliver SL
,
Xing Y,
Chen DH
,
Roh SH,
Pintilie GD
,
Bushnell DA
,
Sommer MH,
Yang E,
Carfi A,
Chiu W
,
Arvin AM
(2020) Nat Commun , 11 , 4141 - 4141
,
Xing Y,
Chen DH
,
Roh SH,
Pintilie GD
,
Bushnell DA
,
Sommer MH,
Yang E,
Carfi A,
Chiu W
,
Arvin AM
(2020) Nat Commun , 11 , 4141 - 4141
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01A102546 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): P41GM103832 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM079429 (United States)
- National Institutes of Health/Office of the Director: S10OD021600 (United States)
