Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-21185
De novo designed tetrahedral nanoparticle T33_dn10 displaying 4 copies of BG505-SOSIP trimer on the surface
EMD-21185
Single-particle4.25 Å
Deposition: 05/01/2020Map released: 22/07/2020
Last modified: 06/03/2024
Sample Organism:
synthetic construct
Sample: De novo designed tetrahedral nanoparticle T33_dn10 displaying 4 copies of BG505-SOSIP trimer on the surface. Nanoparticle consists of 12 copies of both subunits (BG505-SOSIP-T33_dn10A and T33_dn10B)
Fitted models: 6vfk
Deposition Authors: Antanasijevic A
,
Ward AB
Sample: De novo designed tetrahedral nanoparticle T33_dn10 displaying 4 copies of BG505-SOSIP trimer on the surface. Nanoparticle consists of 12 copies of both subunits (BG505-SOSIP-T33_dn10A and T33_dn10B)
Fitted models: 6vfk
Deposition Authors: Antanasijevic A
,
Ward AB
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Antanasijevic A ,
Ueda G ,
Brouwer PJM,
Copps J ,
Huang D ,
Allen JD ,
Cottrell CA ,
Yasmeen A,
Sewall LM ,
Bontjer I,
Ketas TJ,
Turner HL ,
Berndsen ZT ,
Montefiori DC,
Klasse PJ,
Crispin M ,
Nemazee D ,
Moore JP,
Sanders RW ,
King NP ,
Baker D ,
Ward AB
(2020) PLoS Pathog , 16 , e1008665 - e1008665
,
Ueda G ,
Brouwer PJM,
Copps J ,
Huang D ,
Allen JD ,
Cottrell CA ,
Yasmeen A,
Sewall LM ,
Bontjer I,
Ketas TJ,
Turner HL ,
Berndsen ZT ,
Montefiori DC,
Klasse PJ,
Crispin M ,
Nemazee D ,
Moore JP,
Sanders RW ,
King NP ,
Baker D ,
Ward AB
(2020) PLoS Pathog , 16 , e1008665 - e1008665
Grant Support:
- Bill & Melinda Gates Foundation: OPP1115782 (United States)