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EMD-21183
De novo designed icosahedral nanoparticle I53_dn5 presenting BG505-SOSIP, Cryo-EM Map
EMD-21183
Single-particle12.46 Å
Deposition: 05/01/2020Map released: 22/07/2020
Last modified: 02/12/2020
Sample Organism:
synthetic construct
Sample: De novo designed icosahedral nanoparticle I53_dn5 displaying 20 copies of BG505-SOSIP trimer on the surface. Nanoparticle consists of 60 copies of both subunits (BG505-SOSIP-I53_dn5B and I53_dn5A)
Deposition Authors: Ward AB, Antanasijevic A
Sample: De novo designed icosahedral nanoparticle I53_dn5 displaying 20 copies of BG505-SOSIP trimer on the surface. Nanoparticle consists of 60 copies of both subunits (BG505-SOSIP-I53_dn5B and I53_dn5A)
Deposition Authors: Ward AB, Antanasijevic A
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Antanasijevic A 
,
Ueda G ,
Brouwer PJM,
Copps J ,
Huang D ,
Allen JD ,
Cottrell CA ,
Yasmeen A,
Sewall LM ,
Bontjer I,
Ketas TJ,
Turner HL ,
Berndsen ZT ,
Montefiori DC,
Klasse PJ,
Crispin M ,
Nemazee D ,
Moore JP,
Sanders RW ,
King NP ,
Baker D ,
Ward AB
(2020) Plos Pathog. , 16 , e1008665 - e1008665
,
Ueda G ,
Brouwer PJM,
Copps J ,
Huang D ,
Allen JD ,
Cottrell CA ,
Yasmeen A,
Sewall LM ,
Bontjer I,
Ketas TJ,
Turner HL ,
Berndsen ZT ,
Montefiori DC,
Klasse PJ,
Crispin M ,
Nemazee D ,
Moore JP,
Sanders RW ,
King NP ,
Baker D ,
Ward AB
(2020) Plos Pathog. , 16 , e1008665 - e1008665
Grant Support:
- Bill & Melinda Gates Foundation: OPP1115782 (United States)