EMD-21149

Single-particle
3.0 Å
EMD-21149
3D View Gallery
Deposition: 20/12/2019
Map released: 05/08/2020
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-21149

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6vcd summary report (pdf.gz) Map-6vcd FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of IRP2-FBXL5-SKP1 complex

EMD-21149

Single-particle
3.0 Å
EMD-21149
3D View Gallery
Deposition: 20/12/2019
Map released: 05/08/2020
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: IRP2-FBLX5-SKP1 complex
Fitted models: 6vcd

Deposition Authors: Wang H, Shi H
FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster.
Wang H, Shi H , Rajan M, Canarie ER, Hong S , Simoneschi D , Pagano M , Bush MF , Stoll S , Leibold EA, Zheng N
(2020) Mol Cell , 78 , 31 - 41.e5
PUBMED: 32126207
DOI: doi:10.1016/j.molcel.2020.02.011
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: